Hemolytic Uremic Syndrome | Lawyer for HUS Kidney Failure

In the video below, lawyer Fred Pritzker explains hemolytic urmemic syndrome and how it can cause kidney failure. The first section of text is the transcript of the video. There is additional information further down the page.

This video is about hemolytic uremic syndrome, also known as HUS, a dangerous kidney condition that happens when red blood cells are destroyed and block the kidneys’ filtering system. The most common cause of HUS is an E. coli infection resulting from food poisoning.

Hi, my name is Fred Pritzker. My law firm successfully represents people harmed by HUS in foodborne illness cases throughout the United States. We’ve won hundreds of millions of dollars for our foodborne illness clients, including the biggest verdict in history for a victim of HUS.

When a person swallows food laced with E. coli, the bacteria lodges in the gut and produces a dangerous toxin [Shiga toxins]. This toxin can enter the bloodstream and destroy red blood cells, which then clog tiny tubes in the kidneys, causing acute kidney injury.

As the kidneys start to fail, urine output slows or stops altogether. If the damage is significant, the patient may die.

Those with significant kidney damage may go on to develop kidney failure later in life. Sadly, those people will require ongoing dialysis and then kidney transplantation in order to survive.
Even people who survive HUS and return to normal kidney function are at risk for long-term complications. Studies have shown that up to 25% of HUS survivors have developed chronic kidney problems. This means that all people with HUS, especially children, require medical follow-up for years and even decades into the future.

HUS causes serious injury and even death. If you or your child has been diagnosed with HUS, you should contact attorneys with the best record of success and the most experience with HUS cases. Call (1-888-377-8900) the attorneys at Pritzker Hageman today for a free consultation about your HUS case.

Young Children are Most at Risk for Developing HUS from an E. coli Infection

E. coli Bacteria

E. coli magnified 6836x.

Both adults and children can develop hemolytic uremic syndrome, but children are most at risk. Most children who are diagnosed with this disease consumed food contaminated with E. coli O157:H7.  According to some studies, as many as 15 percent of children who are infected with E. coli O157 develop HUS.

Our lawyers help families whose children have HUS. We help them determine

  • if their child is part of an outbreak;
  • what caused the illness (food, water or animal contact);
  • who is legally responsible (food processor, restaurant, etc.).

Past outbreaks have been caused by beef (ground, frozen hamburger patties and mechanically tenderized steak), lettuce, spinach, sprouts, raw (unpasteurized) milk and cheese made from this, unpasteurized apple cider, strawberries, hazelnuts, frozen pizza, other frozen food products, and cookie dough. In some outbreaks, a restaurant is linked to the illnesses, but the food source is not found. When this happens, the restaurant is legally responsible for the harm done by the food it served.

Other types of E. coli can cause this, including non-O157 serotypes O26, O45, O103, O111, O121 and O145. In rare cases, Shigella bacteria can cause HUS.

How Does Hemolytic Uremic Syndrome Cause Kidney Failure?

Hemolytic uremic syndrome (HUS) is a severe complication of E. coli poisoning. It is characterized by damage and destruction of the red blood cells, which leads to a lower than normal number of red blood cells (a condition called anemia), blood clots, and damage to blood vessel walls.

E coli

This is an electron micrograph of a cluster of E. coli, which produce toxins that can cause hemolytic uremic syndrome.

Following intestinal damage from the infection, Shiga toxins created by the bacteria gain access to the blood stream and find their way into the kidneys. There the toxins damage the thin layer of cells that line the interior surface of tiny blood vessels in the glomerulus .  Red blood cells are damaged and make tiny blood clots (thrombi) in the filtering system.  The result is kidney failure and a host of other severe medical problems.

It is impossible to describe just how horrendous this disease is. Little children can have renal failure, strokes, heart attacks and respiratory failure. Some do not survive. This can happen with one bite of tainted food, and companies that sell that food need to be held accountable.

Can Our Family Sue for HUS and E. coli Kidney Failure?

Yes, your family can sue if your child’s illness can be linked to a food product and/or eating establishment (restaurant, deli, cafeteria). Children are most at risk for developing this complication, and they have legal rights. You can sue a corporate wrongdoer on behalf of your child and make sure your son or daughter has the finances needed for a lifetime of medical expenses caused by the sale of unfood. Read: If my child developed HUS from E. coli O157:H7, should we sue?

In a recent trial, attorney Fred Pritzker and his team won $7.55 million for a child with hemolytic uremic syndrome (HUS) who lost 50% of her kidney function and is predicted to require dialysis and kidney transplantation in her early twenties.

Fred Pritzker

Attorney Fred Pritzker can be contacted at 1-888-377-8900 (toll free).

“Acute hemolytic uremic syndrome is generally caused by ingesting food contaminated with E. coli O157:H7 bacteria,” says Fred. “I have had clients, some of them little children, who suffered kidney failure, stroke, heart attack and pancreatitis.  More needs to be done to prevent this devastating illness.”

Attorney Fred Pritzker and his Bad Bug Law Team are some of the few lawyers in the United States with experience winning multi-million-dollar settlements and verdicts.  You can contact Fred using our free consultation form or by calling 1-888-377-8900 (toll free).  Read more: “America’s Food Safety Law Firm.”

Attorney Fred Pritzker has been helping people sickened by contaminated food for decades. He has spoken at Harvard Law School, Cornell University and other venues about food safety. He has also been quoted by The New York Times, The Wall Street Journal, Associated Press, CNN and many others. Contact Fred for a free consultation.

Filing a Lawsuit for Compensation May Be the Only Way to Get Justice

Unlike most countries, the U.S. government generally does not press criminal charges against corporate CEOs and other executives for selling tainted products. This makes filing a personal injury or wrongful death lawsuit even more important. This is often the only way to get any justice.

Our law firm is one of the very few in the U.S. that regularly represents clients, both children and adults, in these cases. Some of our clients have gone on to be food safety advocates, working to make legislative changes and educate the public about foodborne illness. Our E. coli-HUS lawyers regularly speak to various audiences about food safety.

2017 Outbreak News

An E. coli outbreak linked to I.M. Healthy SoyNut Butter products has sickened at least 23 people in 9 states, including several children who developed hemolytic uremic syndrome (HUS), the leading cause of kidney failure in children in the U.S. We just learned that E. coli and HUS  at Montessori of Alameda, Portland, Oregon, are part of the I.M. Healthy SoyNut Butter outbreak.

“The young children sickened in this outbreak are now at risk for future kidney disease, particularly those who developed hemolytic uremic syndrome,” said Brendan Flaherty, a food safety lawyer who recently won $7.55 million for a child who lost 50% of her kidney function and is predicted to require dialysis and kidney transplantation in her early twenties. Contact Brendan at 1-888-377-8900 (toll free).

Our law firm filed an E. coli-HUS lawsuit against The SoyNut Butter Company for one of the 7 children who developed HUS in this outbreak. Attorneys Brendan Flaherty and Ryan Osterholm are representing little M.R., who almost died when his kidneys shut down. If you are a parent and have questions about a lawsuit on behalf of your child, you can contact Brendan and Ryan for a free consultation.

Hemolytic Uremic Syndrome Complications

HUS complications are severe and can include the following:

  • kidney failure requiring hemodialysis
  • strokes
  • encephalopathy
  • acute respiratory distress syndrome
  • pancreatitis
  • diabetes mellitus
  • myocardial infarction
  • cardio myopathy
  • cardiogenic shock
  • congestive heart failure
  • cortical blindness
  • wrongful death.

The damage done by HUS can be permanent, and patients are faced with the risk of future kidney disease. Read: “Long-term consequences of E. coli-HUS kidney failure.”

With careful and aggressive medical attention, the risk of fatality is less than four percent. Up to 30 percent of the children who survive the disease, however, will be left with permanent damage to their kidneys. Children who recover usually do so quickly, while afflicted adults may experience longer recovery times since kidney damage is usually more extensive in adult cases.

Recent studies show that HUS is now the most common cause of renal failure for children in the U.S. It is recommended that people who recover undergo long-term follow-up and observation to monitor for the potential onset of chronic kidney disease, hypertension (high blood pressure), and chronic neurological damage.

Approximately 7,500 cases are diagnosed each year in the U.S.  Read the HUS FAQ page. Read about the symptoms of hemolytic urmic syndrome.

Acute Encephalopathy in a Pregnant Woman

A 26-year-old pregnant woman (31 weeks) contracted an E. coli O111 infection after eating at a restaurant in Japan (see number 6 below, Ito). After 4 days, she was admitted to the hospital with extremely bloody diarrhea and severe abdominal pain.

Upon admittance to the hospital, antibiotics were administered.

The baby was delivered by C-section at 32 weeks. Although small, the baby lived.

The mother, however, went into respiratory arrest and had a heart attack (cardiac arrest). Her resulting Glasgow Coma Scale score was 11. She was diagnosed with HUS and put on hemodiafiltration and plasma exchange therapy.

The damage to her brain was significant. She had diffuse brain cortex damage and acute encephalopathy. When she emerged out of a coma on the 14th day after the C-section, she had to have rehabilitation to recover motor and cognitive functions.

Scientific Literature

Below are a few of the many articles discussing this deadly disease. Our lawyers do a lot of work in this area and keep up with the literature. You can contact one of our lead lawyers to discuss the issues raised in the articles below or your need for legal representation. Call 1-888-377-8900 (toll free) to contact Fred Pritzker, Brendan Flaherty, Ryan Osterholm or Eric Hageman. Because of the severity of this illness, our lawyers, upon invitation by the family, often visit clients in the hospital.

  1. A study looked at 259 children with O157:H7 infections, 36 of whom developed this complication. The researchers concluded that antibiotic use to treat these infections is connected to a higher rate of future HUS. Wong, Craig S., et al. “Risk factors for the HUS in children infected with Escherichia coli O157: H7: a multivariable analysis.” Clinical Infectious Diseases 55.1 (2012): 33-41 9.
  2. Another study concluded that the use of antibiotics may cause this complication. Smith, Kirk E., et al. “Antibiotic treatment of Escherichia coli O157 infection and the risk of HUS, Minnesota.The Pediatric Infectious Disease Journal 31.1 (2012): 37-41.
  3. A higher risk of heart, kidney (renal) and pancreatic disease was found for patients who had experienced kidney failure and needed dialysis treatment. Brunelli, Steven M., et al. “Consequences of HUS among hemodialysis patients.” Journal of Nephrology 28.3 (2015): 361-367.
  4. This article provides a detailed discussion of the risks. This study found that most of the damage occurs in the kidneys: proteinuria [high quantities of protein in the urine]; hypertension [high blood presssure]; chronic kidney disease (CKD); and end-stage kidney disease (ESKD). Other possible health problems include: colonic strictures [narrowing of section of colon], cholelithiasis [gallstones], diabetes mellitus or brain injury. Early dialysis lowered the mortality rate and was associated with overall better recovery and the lowering of future risks. Spinale, Joann M., et al. “Long-term outcomes of Shiga toxin HUS.” Pediatric Nephrology 28.11 (2013): 2097-2105.
  5. This article focuses on central nervous system (CNS) damage, often manifested by seizures and coma. CNS damage, primarily damage to the brain, is the “primary cause of death” in these patients. The center of concern in this article is hydration and its connection to CNS damage. Ardissino, Gianluigi, et al. “Hemoconcentration: a major risk factor for neurological involvement in HUS.” Pediatric Nephrology 30.2 (2015): 345-352.
  6. This is a case report. Ito, M., et al. “Hemolytic–uremic syndrome with acute encephalopathy in a pregnant woman infected with epidemic enterohemorrhagic Escherichia coli: characteristic brain images and cytokine profiles.” International Journal of Infectious Diseases 34 (2015): 119-121.